Oxytocin May be Superior to Gliptins as a Potential Treatment for Diabetic COVID-19 Patients

Phuoc-Tan Diep


Diabetes is a comorbidity associated with an increased risk of severe COVID-19. Gliptins are anti-diabetic drugs that inhibit dipeptidyl peptidase-4 (DPP4) and they have been proposed as a possible treatment for COVID-19 patients with and without diabetes due to their immunomodulatory properties. Oxytocin has also been proposed as a treatment for COVID-19 due to its immunomodulatory properties as well as other mechanisms. In addition, oxytocin has been identified as a natural DPP4 inhibitor. Therefore, oxytocin not only has the properties associated with DPP4 inhibition but it has numerous additional beneficial properties. It is proposed that oxytocin may be superior to DPP4 inhibitors for COVID-19 patients especially for patients with type 2 diabetes.


Doi: 10.28991/SciMedJ-2020-02-SI-10

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Dipeptidyl Peptidase-4; DPP4 Inhibitor; Oxytocin; Diabetes; COVID-19; SARS-CoV-2.


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DOI: 10.28991/SciMedJ-2020-02-SI-10


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